Accutest Uriscreen™ is a rapid screening test which combines the detection of both bacteriuria and pyuria (the presence of somatic cells in urine), by detecting catalase activity (an enzyme present in many eukaryotic cells). Accutest Uriscreen™ provides physicians’ offices, clinical laboratories and outpatient sites with a rapid and accurate screening method for urinary tract infections. Accutest Uriscreen’s negative predictive value (NPV) of  95%, is higher than the NPV of the urine dipstick. Accutest Uriscreen™ is a cost-effective, screening procedure, which can be used to complement conventional culture methods.

• Ideal for screening of UTI in physicians’ offices, long term and urgent care settings.
• Efficient way to screen out negative specimens and determine need for further testing.
• Early diagnosis prevents unnecessary treatment and minimizes costly complications of UTI.
• Visual results within 2 minutes
• Easy to use; requires no instrumentation
• Perfect UTI screen for outpatient settings
• Improved performance over routine urinalysis
• Exceptionally sensitive for low bacterial counts
• (5×104 CFU/ml at 93% sensitivity)
• Early diagnosis prevents unnecessary treatment and minimizes costly complications of UTI
• CPT Code: 81007QW

FEATURES & BENEFITS

• Visual results within 2 minutes
• Easy to use; requires no instrumentation
• Perfect UTI screen for outpatient settings
• Ideal for screening patients for UTIs upon admission to a hospital or acute care facility
• Improved performance over routine urinalysis
• Exceptionally sensitive for low bacterial counts(5×104 CFU/ml at 93% sensitivity)
• Efficient way to screen out negative specimens and determine the need for further testing
• Early diagnosis prevents unnecessary treatment and minimizes costly complications of UTI

STUDIES AND SUMMARIES

A Rapid Enzymatic Screening Test – Journal of Clinical Microbiology

https://jcm.asm.org/content/jcm/30/3/680.full.pdf

 The discussion section states:

“A multicenter study was performed to evaluate the ability of the URISCREEN a 2-min catalase tube test, to detect bacteriuria and pyuria. This test was compared with the Chemstrip LN (BioDynamics, Division of Boehringer Mannheim Diagnostics, Indianapolis, Ind.), a 2-min enzyme dipstick test; a semiquantitative plate culture method was used as the reference test for bacteriuria, and the Gram stain or a quantitative chamber count method was used as the reference test for pyuria. Each test was evaluated for its ability to detect probable pathogens at .102 CFU/ml and/or .1 leukocyte per oil immersion field, as determined by the Gram stain method, or >10 leukocytes per ,ul, as determined by the quantitative count method. A total of 1,500 urine specimens were included in this evaluation. There were 298 specimens with 102 CFU/ml and 451 specimens with pyuria. Of the 298 specimens with probable pathogens isolated at various colony counts, 219 specimens had colony counts of 2 105 CFU/ml, 51 specimens had between 104 and 105 CFU/ml, and 28 specimens had between 102 and < 0.05).”

The 2004 USPSTF evidence update on screening for asymptomatic bacteriuria (7) highlighted the Uriscreen (Savyon Diagnostics, Ashdod, Israel) enzymatic screening test as having good potential because of its reported 100% sensitivity and negative predictive value in 1 study of 313 consecutive pregnant patients in Israel. 

Other Studies

Select any of the studies below to find out more information:

ScienceDirect: Uriscreen, A Rapid Enzymatic Urine Screening Test

PubMed.gov: Uriscreen, A Useful Predictor of Significant Bacteriuria in Pregnancy 

Study: The Validity of the Uriscreen Test for Early Detection of Urinary Tract Infection in Children

Lab Medicine: Evaluation of Two Rapid Urine Screening Tests